ESGLD workshop and graduate course 2015 materials

This page contains the available content from the 2015 ESGLD Workshop and Graduate course. Click to see the link to the full  2015 Agenda here.

30th September

1st session

  • Biogenesis of Lysosomes (Diego Medina) (link)
  • Endocytotic delivery route to lysosomes (Judith Klumperman (link)
  • Lysosomal membrane proteins: an overview and non-transporter / non-channel
    proteins (Markus Damme (link)

2nd session

  • Transporters and Ion Channels (Bruno Gasnier and Tobias Stauber(link)
  • Autophagy (Carmine Settembre(link)
    • A video on Autophagy (link)

1st October

1st session

  • Lipid degradation and lipid storage diseases (Timothy Cox(link)
  • Glycosaminoglycan degradation and mucopolysaccaridoses (Giancarlo Parenti(link)

2nd session

  • Therapy of lysosomal storage diseases (Brian Bigger(link)

Journal club

  • LIMP-2 is a receptor for lysosomal mannose-6-phosphate-independent targeting of beta-glucocerebrosidase (link)
  • Biology of the lysosome (link)
  • Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice (link)
  • RIPK3 as a potential therapeutic target for Gaucher’s disease (link)
  • Therapy of lysosomal storage diseases (LSDs) (link)
  • TFEB links autophagy to Lysosomal Biogenesis (link)
  • A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB (link)