ESGLD… Welcome to the
News Archive Section
Here you will find articles about forthcoming and previous events, job vacancies, information regarding visiting scholarships and other assorted news items.
ESGLD are seeking…
New Board Members…
Dear ESGLD Members,
I hope you are all well and those who attended enjoyed our recent workshop and graduate course!
I am writing to inform you that two of our long standing board members have decided to step down and therefore we would like to invite the membership to propose new ESGLD board candidates. The plan will be to hold an AGM in December (date tbc) and ask the members to vote for their preferred candidates. If you have someone that you would like to propose please email firstname.lastname@example.org who will compile a list of candidates. It is essential that each candidate has a proposer and a seconder so please include both on your email.
The ESGLD Board would like to sincerely thank Prof. Eeva-liisa Eskelinen and Prof Andrea Ballabio for all their hard work on the board over the last few years.
I would also like to let the membership know that I have decided to step down as Chairman after 9 years in post. I will continue on the ESGLD board but feel it is time for a new chairperson to guide the group going forward. I will stay as caretaker chairman until a new chair is appointed.
Brian Bigger, ESGLD Chair
A Big Thank You
We would like to say a big THANK YOU to everyone who participated in the recent 24th ESGLD Workshop and Graduate Course. It was great to have an in-person meeting again to discuss our science and meet old (and new) friends.
We would like to take this opportunity to congratulate our Prize Winners once again!
Best Oral Presentations:
Catarina Pechincha – The lysosomal enzyme trafficking factor LYSET enables nutrient generation from extracellular proteins.
Fabio Catalano – Brain targeting of GAA Promotes Full Correction of Murine Pompe Disease at a Clinically Relevant Dosage of Lentiviral Gene Therapy.
Edoardo Ratto – Direct control of lysosomal catabolic activity by mTORC1 through regulation of V-ATPase assembly.
Jan van der Beek – Loss of the HOPS complex induces hybrid early-late endosomes that accumulate endocytic, biosynthetic and autophagic cargo.
Best Flash talk groups exercise:
Catarina Pechincha, Drosos Katsavelis, Anastasia Laudicina
See you in Israel in 2024!
On behalf of the organising committee,
24th ESGLD Workshop and Graduate Course
BOOKINGS NOW OPEN…
Dear ESGLD members,
The ESGLD Chairman, Local Organising Committee and Scientific Committee are happy to announce that Registration and Abstract submission for the 24th ESGLD Workshop and Graduate Course to be held face to face in Lancaster, UK between 7th – 11th September 2022 is now open!!!
Key meeting dates:
7th – 8th September 2022: Graduate course
8th – 11th September 2022: 24th ESGLD workshop
Please go to www.esgld.org to check your lab membership (100 Euros) is up-to-date for the period 2022/2023 – this allows ALL members of your lab to register for the 24th ESGLD Workshop and Graduate Course.
For details of this event and to register and submit your abstracts please follow this link BOOK NOW
Abstract submission deadline is 1st August 2022 – go direct using this ABSTRACT SUBMISSION LINK.
For any queries about the 24th ESGLD Workshop and Graduate Course please contact: email@example.com
We look forward to seeing you there!
Thank you for your continued collaboration and support,
Brian Bigger Chairman ESGLD chairman@ESGLD.org
Pim Pijnappel Treasurer ESGLD treasurer@ESGLD.org
Paul Saftig Secretary ESGLD secretary@ESGLD.org
Please email Chairman for website enquiries, Treasurer for payment enquiries and Secretary for new membership enquiries.
24th ESGLD Workshop & Graduate Course – UK 7th-11th September 2022
Dear ESGLD Members, as you may know it is the turn of the UK to hold the Bi-Annual ESGLD Workshop and Graduate Course. ESGLD Chair, Professor Brian Bigger and his University of Manchester Team are happy to announce that a date has been set for this event which will take place in the Northwest of England. Please hold the 7th – 11th of September 2022 in your diaries!
Valuable Lysosomal Data made available again!
Original lysosomal membrane proteomics data accessible again
Dear ESGLD Members we are happy to let you know that the original data in the proteomics paper on human lysosomal membrane by Bernd Schröder et al. (Integral and Associated Lysosomal Membrane Proteins. Traffic Volume8, Issue12 December 2007, Pages 1676-1686) is now available again.
These data became inaccessible after Blackwell’s, the original publishing house of Traffic, had been discontinued, for quite a long time. Thanks to the efforts of editors with Willey, the present publisher of Traffic, all the original data are accessible again. Just click on “Supporting information” at the end of the paper, if you ever wished to see them and could not to.
There is extensive original data including sequence of more than 13 thousands identified peptides and various data evaluations that are available. Please see link HERE:
MPSII Clinical Trial Project Manager
University of Manchester are seeking to appoint a full-time Clinical Trial Project Manager to work on an academic gene therapy clinical trials for MPSII patients. The posts is available for an immediate start for a fixed term period for 3 years.
The position offers an ideal opportunity for an enthusiastic, well-motivated individual to work as part of a multi-disciplinary team to manage and ensure the success of this gene therapy clinical trial in MPSII patients. This CTIMP trial require an ambitious Project Manager to manage the set up and day to day running’s of the trial, liaising with the sponsor, clinical site, managing CRO and other third parties.
The post holder will also support the development of other new and ongoing clinical trials within the group and provide administrative support in the submission of industrial funding bids, grant applications and support the set up and running of a GCP facility. The post holder will have excellent interpersonal, communication, IT, and organisational skills, will be able to work with minimal supervision, and will have experience within research, preferably in biological or medical sciences within a trial setting. Adherence to good clinical practice (GCP) is essential to this role, particularly with regard to data handling and record keeping.
As an equal opportunities employer we welcome applicants from all sections of the community regardless of age, sex, gender (or gender identity), ethnicity, disability, sexual orientation and transgender status. All appointments are made on merit.
For further detail please follow link HERE:
Commemoration Meeting Prof. Milan Elleder – 5th October 2021
A Commemoration meeting is to be held on the 5th of October 2021 to honour the memory of Professor Milan Elleder. It has been 10 years since he passed away. The meeting information is in the invitation – please click the link below.
There will be a Keynote lecture from Dr. Marie T Vanier (INSERM, Lyon, France) – Milan Elleder, the Prague group and Niemann-Pick diseases. It will be a good opportunity to meet to honour the memory of Professor Elleder the way we think he would like. The majority of the presentations are going to be in Czech but the Keynote lecture from Dr Vanier will be in English at 11:15-12:30 (CEST) and this is the link to the live stream (https://bit.ly/setkanielleder).
Milan Elleder was a key ESGLD figure for several decades and has contributed substantially to the community. Also, Marie Vanier´s keynote tribute to his contributions to understanding and delineation of NPA/B and NPC will be quite exceptional and of major interest to “lysosomalists” of all ages.
Also attached is Milan Elleder´s obituary that was written by Martin Hrebicek and was distributed to ESGLD members in 2011.
elleder_invitation (Link to event Invitation)
orbituaryElleder (Link to Obituary written by Martin Hrebicek)
MPSIIIA and MPSII Clinical Trial Project Manager Roles x 2 – deadline 6/10/21
University of Manchester are seeking to appoint two full-time Project Managers to work on two academic gene therapy clinical trials for either MPSII or MPSIIIA patients. The posts are both available for an immediate start for a fixed term period until the 30th October 2024.
The position offers an ideal opportunity for an enthusiastic, well-motivated individual to work as part of a multi-disciplinary team to manage and ensure the success of this gene therapy clinical trial in MPSII or MPSIIIA patients. Both trials require an ambitious Project Manager to manage the day to day runnings of the trial, liaising with the Sponsor, Clinical site, managing CRO and other third parties.
You will also support the development of other new and ongoing clinical trials within the group and provide administrative support in the submission of industrial funding bids, grant applications and support the set up and running of a GCP facility. The post holder will have excellent interpersonal, communication, IT, and organisational skills, will be able to work with minimal supervision, and will have experience within research, preferably in biological or medical sciences. Adherence to good clinical practice (GCP) is essential to this role, particularly with regard to data handling and record keeping.
For More information please follow this HERE:
ESGLD Virtual Summer Meeting – Thanks and Awards
A big thanks to everyone who took part in our recent ESGLD Summer Virtual Meeting. We had a great turnout and a particular thanks to all our excellent speakers who made it such a success.
Talks over the three days covered a broad spectrum of topics including lysosomal function, mechanisms of lysosomal disease and therapies and diagnosis. The ESGLD Scientific Committee had the difficult task of choosing four outstanding presentations. Three prizes were awarded for the best presentations from the selected abstracts and one prize for the best flash talk.
Awards for best selected abstract presented to:
Alessia Calcagni (Baylor College of Medicine ) – CLN3 protein is at the crossroad between the biosynthetic/secretory compartment and lysosomes
Malte Klüssendorf (University Medical Center, Hamburg-Eppendorf) Cytosoplasmic retention of acetylated transcription factor EB
Dominic Winter (University of Bonn) Characterization of Lysosomal Protein Interactions and Structures by Cross Linking Mass Spectrometry
Award for best Flash Talk/Virtual Poster presented to:
S.L.M. in ‘t Groen (Erasmus MC) – Uncovering pathological mechanisms in Pompe disease using a 3D-skeletal-muscle-on-a-chip system.
For further information please contact:
Prof. Dr. Paul Saftig
Tel: ++ 49-(0)431-8802216